Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
, 12, 139

Disease Management for Co-Morbid Depression and Anxiety in Diabetes Mellitus: Design of a Randomised Controlled Trial in Primary Care

Affiliations
Randomized Controlled Trial

Disease Management for Co-Morbid Depression and Anxiety in Diabetes Mellitus: Design of a Randomised Controlled Trial in Primary Care

Corinne H Stoop et al. BMC Fam Pract.

Abstract

Background: Depression and anxiety are common co-morbid health problems in patients with type 2 diabetes. Both depression and anxiety are associated with poor glycaemic control and increased risk of poor vascular outcomes and higher mortality rates. Results of previous studies have shown that in clinical practice, treatment of depression and anxiety is far from optimal as these symptoms are frequently overlooked and undertreated.

Methods/design: This randomised controlled trial will examine the effectiveness of a disease management programme treating symptoms of depression and anxiety in primary care patients with Type 2 diabetes. Patients will be randomized on patient level in 1:1 ratio. Random block sizes of 2 and 4 are used. The disease management programme consists of screening, stepped treatment and monitoring of symptoms (n = 80). This will be compared to care as usual (n = 80).

Discussion: The disease management model for co-morbid depression and anxiety in primary care patients with diabetes is expected to result in reduced symptoms of depression and anxiety, improved quality of life, reduced diabetes specific distress and improved glyceamic control, compared to care as usual.

Trial registration: Dutch Trial Register NTR2626.

Figures

Figure 1
Figure 1
DiMaCoDeA Intervention.

Similar articles

See all similar articles

Cited by 3 articles

References

    1. Fact sheet No 312 Diabetes. http://www.who.int/mediacentre/factsheets/fs312/en/
    1. Ali S, Stone MA, Peters JL, Davies MJ, Khunti K. The prevalence of co-morbid depression in adults with Type 2 diabetes: a systematic review and meta-analysis. Diabet Med. 2006;23:1165–1173. doi: 10.1111/j.1464-5491.2006.01943.x. - DOI - PubMed
    1. Bouwman V, Adriaanse MC, van't Riet E, Snoek FJ, Dekker JM, Nijpels G. Depression, anxiety and glucose metabolism in the general dutch population: the new Hoorn study. PLoS One. 2010;5:e9971. doi: 10.1371/journal.pone.0009971. - DOI - PMC - PubMed
    1. Lin EH, Korff MV, Alonso J, Angermeyer MC, Anthony J, Bromet E, Bruffaerts R, Gasquet I, de Girolamo G, Gureje O. et al. Mental disorders among persons with diabetes--results from the World Mental Health Surveys. J Psychosom Res. 2008;65:571–580. doi: 10.1016/j.jpsychores.2008.06.007. - DOI - PMC - PubMed
    1. Grigsby AB, Anderson RJ, Freedland KE, Clouse RE, Lustman PJ. Prevalence of anxiety in adults with diabetes: a systematic review. J Psychosom Res. 2002;53:1053–1060. doi: 10.1016/S0022-3999(02)00417-8. - DOI - PubMed

Publication types

Feedback