Going with the flow: an elegant model for symmetry breaking

Rebecca Bastock; Daniel St Johnston

doi:10.1016/j.devcel.2011.11.015

Going with the flow: an elegant model for symmetry breaking

Dev Cell. 2011 Dec 13;21(6):981-2. doi: 10.1016/j.devcel.2011.11.015.

Authors

Rebecca Bastock¹, Daniel St Johnston

Affiliation

¹ The Gurdon Institute and Department of Genetics, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.

PMID: 22172666
DOI: 10.1016/j.devcel.2011.11.015

Abstract

The entry of the sperm centrosome polarizes the anterior-posterior axis of the C. elegans zygote by inducing the formation of complementary cortical Par protein domains. Recent papers from the Seydoux and Grill laboratories (Goehring et al., 2011b and Motegi et al., 2011) reveal how two different symmetry-breaking mechanisms produce the same final pattern through interactions between Par proteins.

Publication types

Comment

Grants and funding

080007/Wellcome Trust/United Kingdom