A ratiometric fluorescent chemodosimeter for Cu(II) in water with high selectivity and sensitivity

Kai Li; Na Li; Xiaotong Chen; Aijun Tong

doi:10.1016/j.aca.2011.10.066

A ratiometric fluorescent chemodosimeter for Cu(II) in water with high selectivity and sensitivity

Anal Chim Acta. 2012 Jan 27:712:115-9. doi: 10.1016/j.aca.2011.10.066. Epub 2011 Nov 15.

Authors

Kai Li¹, Na Li, Xiaotong Chen, Aijun Tong

Affiliation

¹ Department of Chemistry, Tsinghua University, Beijing, China.

PMID: 22177073
DOI: 10.1016/j.aca.2011.10.066

Abstract

Coumarin derivative 1 was synthesized as an efficient ratiometric chemodosimeter for the detection of Cu(II) in 99% water/DMSO (v/v) at pH 7.0. Mechanism studies suggested that 1 formed a complex with Cu(II) at 2:1 ratio accompanied by quenching of green fluorescence at 524 nm; when the solution was heated to 50°C for 30 min, Cu(II)-promoted hydrolysis of coumarin lactone moiety of 1 occurred with bright blue fluorescence at 451 nm emerged. With fluorescence intensity ratio detection at 451 nm and 524 nm, 1 features an excellent sensitivity with the detection limit of 15 nmol L(-1) toward Cu(II) and a good selectivity over other metal ions.