Cutaneous scarring: Pathophysiology, molecular mechanisms, and scar reduction therapeutics Part II. Strategies to reduce scar formation after dermatologic procedures

J Am Acad Dermatol. 2012 Jan;66(1):13-24; quiz 25-6. doi: 10.1016/j.jaad.2011.08.035.


The evidence base underpinning most traditional scar reduction approaches is limited, but some of the novel strategies are promising and accumulating. We review a number of commonly adopted strategies for scar reduction. The outlined novel agents are paradigmatic of the value of translational medical research and are likely to change the scenery in the much neglected but recently revived field of scar reduction therapeutics.

Publication types

  • Review

MeSH terms

  • Bandages
  • Cicatrix / physiopathology*
  • Cicatrix / prevention & control
  • Cicatrix / therapy*
  • Cicatrix, Hypertrophic / physiopathology
  • Cicatrix, Hypertrophic / prevention & control
  • Cicatrix, Hypertrophic / therapy
  • Dermatologic Agents
  • Humans
  • Keloid / physiopathology
  • Keloid / prevention & control
  • Keloid / therapy
  • Risk Factors
  • Skin / physiopathology*
  • Wound Healing / drug effects


  • Dermatologic Agents