PopDrowser: the Population Drosophila Browser

Bioinformatics. 2012 Feb 15;28(4):595-6. doi: 10.1093/bioinformatics/btr691. Epub 2011 Dec 15.

Abstract

Motivation: The completion of 168 genome sequences from a single population of Drosophila melanogaster provides a global view of genomic variation and an understanding of the evolutionary forces shaping the patterns of DNA polymorphism and divergence along the genome.

Results: We present the 'Population Drosophila Browser' (PopDrowser), a new genome browser specially designed for the automatic analysis and representation of genetic variation across the D. melanogaster genome sequence. PopDrowser allows estimating and visualizing the values of a number of DNA polymorphism and divergence summary statistics, linkage disequilibrium parameters and several neutrality tests. PopDrowser also allows performing custom analyses on-the-fly using user-selected parameters.

Availability: PopDrowser is freely available from http://PopDrowser.uab.cat.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biological Evolution
  • Drosophila / classification
  • Drosophila / genetics*
  • Drosophila Proteins / genetics
  • Drosophila melanogaster / genetics*
  • Genetic Variation
  • Genetics, Population
  • Internet
  • Linkage Disequilibrium
  • Polymorphism, Genetic

Substances

  • Drosophila Proteins