Abstract
The paper gives an assessment of the association of structural-functional (histological and cytological), cytogenetic, and cytotoxic changes in the analysis of various exposures of the body during both experiments (oral acrylamide) and population examinations (impact of pulp-and-paper mill waste on the nasal and oral mucosae). The assessment of the association of the study parameters is shown to serve to more completely objectify the pattern of actuating factors.
MeSH terms
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Acrylamide / toxicity*
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Administration, Oral
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Adolescent
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Air Pollutants / toxicity*
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Animals
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Chemical Industry*
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Child
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Cytogenetic Analysis
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Epithelial Cells / drug effects
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Epithelial Cells / pathology
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Humans
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Lethal Dose 50
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Leukocyte Count
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Leukocytes / drug effects
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Leukocytes / pathology
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Male
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Micronuclei, Chromosome-Defective / chemically induced
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Mouth Mucosa / drug effects*
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Mouth Mucosa / pathology
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Nasal Mucosa / drug effects*
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Nasal Mucosa / pathology
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Rats
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Thyroid Gland / drug effects*
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Thyroid Gland / pathology
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Thyroid Gland / surgery
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Thyroidectomy
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Toxicity Tests
Substances
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Air Pollutants
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Acrylamide