The epigenotype. 1942

Int J Epidemiol. 2012 Feb;41(1):10-3. doi: 10.1093/ije/dyr184. Epub 2011 Dec 20.


The adult characteristics of animals, i.e. their phenotypes, must be studied in order to reach conclusions about the genotypes, i.e. the hereditary constitutions which form the basic subject-matter of genetics. But between genotype and phenotype lies a whole complex of development processes, for which Dr Waddington proposes the name 'epigenotype.' He here describes some of the general characteristics of an epigenotype, with special reference to the fruit-fly Drosophila melanogaster.

Publication types

  • Biography
  • Classical Article
  • Historical Article

MeSH terms

  • Animals
  • Drosophila melanogaster / genetics*
  • Epigenesis, Genetic*
  • Genotype*
  • History, 20th Century
  • Phenotype*

Personal name as subject

  • C H Waddington