The short-term effects of air pollution on adolescent lung function in Taiwan

Chemosphere. 2012 Mar;87(1):26-30. doi: 10.1016/j.chemosphere.2011.11.048. Epub 2011 Dec 19.


A mass screening of lung function associated with air pollutants for children is limited. This study assessed the association between air pollutants exposure and the lung function of junior high school students in a mass screening program in Taipei city, Taiwan. Among 10,396 students with completed asthma screening questionnaires and anthropometric measures, 2919 students aged 12-16 received the spirometry test. Forced vital capacity (FVC) and forced expiratory flow in 1s (FEV(1)) in association with daily ambient concentrations of particulate matter with diameter of 10 μm or less (PM(10)), sulfur dioxide (SO(2)), carbon monoxide (CO), nitrogen dioxide (NO(2)), and ozone (O(3)) were assessed by regression models controlling for the age, gender, height, weight, student living districts, rainfall and temperature. FVC, had a significant negative association with short-term exposure to O(3) and PM(10) measured on the day of spirometry testing. FVC values also were reversely associated with means of SO(2), O(3), NO(2), PM(10) and CO exposed 1 d earlier. An increase of 1-ppm CO was associated with the reduction in FVC for 69.8 mL (95% CI: -115, -24.4 mL) or in FEV(1) for 73.7 mL (95% CI: -118, -29.7 mL). An increase in SO(2) for 1 ppb was associated with the reductions in FVC and FEV(1) for 12.9 mL (95% CI: -20.7, -5.09 mL) and 11.7 mL (95% CI: -19.3, -4.16 mL), respectively. In conclusion, the short-term exposure to O(3) and PM(10) was associated with reducing FVC and FEV(1). CO and SO(2) exposure had a strong 1-d lag effect on FVC and FEV(1).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Air Pollutants / analysis
  • Air Pollutants / toxicity*
  • Air Pollution / adverse effects
  • Air Pollution / statistics & numerical data
  • Carbon Monoxide / analysis
  • Carbon Monoxide / toxicity
  • Child
  • Environmental Monitoring
  • Female
  • Humans
  • Inhalation Exposure / adverse effects*
  • Inhalation Exposure / statistics & numerical data
  • Lung / drug effects*
  • Lung / physiology
  • Male
  • Ozone / analysis
  • Ozone / toxicity
  • Particulate Matter / analysis
  • Particulate Matter / toxicity
  • Respiratory Function Tests
  • Sulfur Dioxide / analysis
  • Sulfur Dioxide / toxicity
  • Taiwan


  • Air Pollutants
  • Particulate Matter
  • Sulfur Dioxide
  • Ozone
  • Carbon Monoxide