Frequency of peripherally inserted central catheter complications in children

Pediatr Infect Dis J. 2012 May;31(5):519-21. doi: 10.1097/INF.0b013e31824571b0.


This study examined the frequency and types of complications with peripherally inserted central catheters (PICCs) placed in immunocompetent pediatric patients for parenteral antimicrobial therapy. It also sought to determine risk factors associated with those complications. Complications occurred at a frequency of 19.3/1000 PICC days, and greater than 30% of PICCs developed at least one complication. Risk factors for complication include double-lumen PICCs, PICCs placed in the femoral vein, younger age, and greater number of daily doses.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Catheter-Related Infections / epidemiology*
  • Catheter-Related Infections / microbiology
  • Catheterization, Central Venous / adverse effects*
  • Catheterization, Peripheral / adverse effects*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Immunocompetence
  • Infant
  • Infusions, Parenteral
  • Male
  • Risk Factors
  • Thrombosis / epidemiology*


  • Anti-Bacterial Agents