Long-term follow-up of patients with postural tachycardia syndrome

Clin Auton Res. 2012 Jun;22(3):151-3. doi: 10.1007/s10286-011-0155-1. Epub 2011 Dec 22.


Postural tachycardia syndrome (POTS) refers to the presence of orthostatic intolerance symptoms with a heart rate increment ≥ 30 bpm, usually up to ≥ 120 bpm. Pathophysiology and POTS's clinical presentation are heterogeneous and its prognosis is uncertain. We reviewed the major clinical characteristics of POTS patients and assessed their long-term follow-up. Our series results, one with the longest follow-up, illustrate POTS as a clinical entity with variable, but usually benign outcome, in which most patients can reassume their daily activities without great limitations, after proper diagnosis and treatment are made.

MeSH terms

  • Adult
  • Autonomic Nervous System Diseases / diagnosis*
  • Autonomic Nervous System Diseases / drug therapy
  • Autonomic Nervous System Diseases / physiopathology*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Orthostatic Intolerance / diagnosis*
  • Orthostatic Intolerance / drug therapy
  • Orthostatic Intolerance / physiopathology*
  • Postural Orthostatic Tachycardia Syndrome / diagnosis*
  • Postural Orthostatic Tachycardia Syndrome / drug therapy
  • Postural Orthostatic Tachycardia Syndrome / physiopathology*
  • Retrospective Studies
  • Young Adult