Successful use of rifampicin in the treatment of tuberculosis in renal transplant patients immunosuppressed with cyclosporine

Transplantation. 1990 Oct;50(4):597-8. doi: 10.1097/00007890-199010000-00014.

Abstract

Cyclosporine and rifampicin were used simultaneously in 6 renal transplant patients with tuberculosis. The total daily dose of cyclosporine had to be increased 3-5 fold, with the frequency of administration increased from twice to thrice daily. With this regimen, satisfactory cyclosporine levels were attained and there was no adverse affect on graft function.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cyclosporins / administration & dosage*
  • Cyclosporins / blood
  • Cyclosporins / therapeutic use
  • Drug Administration Schedule
  • Drug Interactions
  • Female
  • Humans
  • Kidney Transplantation*
  • Male
  • Rifampin / administration & dosage*
  • Rifampin / therapeutic use
  • Tuberculosis, Pulmonary / drug therapy*

Substances

  • Cyclosporins
  • Rifampin