Prevention and management of cataracts in children with juvenile idiopathic arthritis-associated uveitis

Curr Rheumatol Rep. 2012 Apr;14(2):142-9. doi: 10.1007/s11926-011-0229-z.

Abstract

Juvenile idiopathic arthritis (JIA)-associated uveitis can be associated with vision-compromising complications such as cataracts, glaucoma, synechiae, and band keratopathy. Of these, cataracts are one of the most common sequelae of JIA-associated uveitis and can result in significant visual disability. Risk factors for cataracts include posterior synechiae and longstanding ocular inflammation. Prevention of cataract development is crucial through appropriate control of uveitis. However, not all preventive measures are successful, and further management consisting of medical and surgical techniques is often necessary. Various factors should be taken into consideration when deciding on cataract management, including timing of surgery and placement of an intraocular lens. Continued partnership between pediatric rheumatologists and pediatric ophthalmologists can help ensure favorable visual outcomes.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Arthritis, Juvenile / complications*
  • Cataract / drug therapy*
  • Cataract / etiology
  • Cataract / prevention & control*
  • Child
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Risk Factors
  • Uveitis / complications*
  • Visual Acuity

Substances

  • Immunosuppressive Agents