Sporothrix schenckii Cell Wall Peptidorhamnomannans

Front Microbiol. 2011 Dec 21;2:243. doi: 10.3389/fmicb.2011.00243. eCollection 2011.


This mini-review article is dedicated to clarifying certain important biochemical aspects of Sporothrixschenckii cell wall peptidorhamnomannans. Cell wall components involved in the host interaction such as antigens as well as a gp70 adhesin are important molecules present on the surface of the yeast parasitic phase. Other structural glycoconjugates present on the fungus cell surface are also described here. Knowledge of the fine structure of carbohydrate epitopes expressed on the surface in both morphological phases of S. schenckii permitted the development of non-invasive immunochemical methods to diagnose human and feline sporotrichosis.

Keywords: Sporothrix schenckii; antigens; cell wall; gp70; peptidorhamnomannan.