Making enhancers from spare parts of the genome

Genome Biol. 2011 Dec 29;12(12):138. doi: 10.1186/gb-2011-12-12-138.

Abstract

New studies show that novel long-range enhancers of developmental genes can emerge by exaptation of protein-coding sequences with no previous regulatory function.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biological Evolution
  • Conserved Sequence
  • Enhancer Elements, Genetic*
  • Exons / genetics
  • Gene Duplication
  • Genes, Developmental*
  • Genes, Regulator*
  • Genome*
  • Humans
  • Mice
  • Sharks
  • Smegmamorpha