Comparative study of the effect of dexamethasone injection and consumption in lower third molar surgery

Int J Oral Maxillofac Surg. 2012 Feb;41(2):244-7. doi: 10.1016/j.ijom.2011.12.011. Epub 2011 Dec 28.

Abstract

The aim of this study was to compare the effect of intramuscular (IM) injection and consumption of 8 mg dexamethasone in patients after lower third molar (LTM) surgery. 20 healthy Thai patients, average age 20 years, with bilateral LTM removal were recruited for this study, a double blinded, paired sample clinical trial. The washout period was 1 month after the first operation. Clinical assessment of facial swelling, pain and maximum mouth opening were measured before and after operation for 7 days. No significant difference was found in facial swelling between IM injection and consumption of 8 mg dexamethasone after LTM surgery (paired t test P>0.05). The visual analogue scale scores for pain assessment showed no significant difference between IM injection and consumption of dexamethasone (paired t test P>0.05). The results conclude that IM injection or consumption of dexamethasone after LTM surgery can be used to control facial swelling, pain and trismus.

Publication types

  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Administration, Oral
  • Adolescent
  • Anti-Inflammatory Agents / administration & dosage*
  • Dexamethasone / administration & dosage*
  • Double-Blind Method
  • Edema / prevention & control
  • Facial Pain / prevention & control
  • Female
  • Follow-Up Studies
  • Glucocorticoids / administration & dosage*
  • Humans
  • Injections, Intramuscular
  • Male
  • Mandible / surgery*
  • Molar, Third / surgery*
  • Pain Measurement
  • Pain, Postoperative / prevention & control
  • Placebos
  • Postoperative Complications / prevention & control
  • Range of Motion, Articular / physiology
  • Tooth Extraction / methods*
  • Tooth, Impacted / surgery*
  • Trismus / prevention & control
  • Young Adult

Substances

  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Placebos
  • Dexamethasone