Deconstructing hepatitis C virus infection in humanized mice

Ann N Y Acad Sci. 2011 Dec;1245:59-62. doi: 10.1111/j.1749-6632.2011.06317.x.

Abstract

Hepatitis C virus is a major medical problem. Novel small-animal models are likely to accelerate the development of more effective therapeutics and a vaccine.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Physiological
  • Animals
  • Disease Models, Animal
  • Hepacivirus / pathogenicity
  • Hepacivirus / physiology
  • Hepatitis C / etiology*
  • Host-Pathogen Interactions / genetics
  • Host-Pathogen Interactions / physiology
  • Humans
  • Mice
  • Tissue Engineering
  • Transplantation, Heterologous