Changes in cardiovascular risk factors and inflammatory markers of young, healthy, men after six weeks of moderate or high intensity resistance training

J Sports Med Phys Fitness. 2011 Dec;51(4):695-700.


Aim: The present study was done to see the Influence of moderate and severe intensity resistance exercises on some cardiovascular risk factors.

Methods: Thirty young healthy male were randomly divided in to two types of intervention [MI: moderate intensity (45-55% 1RM), HI: high intensity (80-90% 1RM)] and one Control (no intervention) groups. Subjects in MI and HI intervention groups underwent 3 supervised resistance-training sessions per week for six weeks. IL-1, IL-6, HS-CRP, fibrinogen, ApoB, ApoA, LDL, HDL, ApoB/ApoA ratio, Lipoprotein Lipase (LPL), TG, cholesterol, cholesterol/HDL ratio, body mass index (BMI), systolic pressure (Ps), diastolic pressure (Pd) and waist/hip ratio (WHR) before and after resistance training period were assessed.

Results: IL-1, IL-6, ApoB, ApoA, LPL, TG levels, ApoB/ApoA ratio, Ps, Pd, WHR, BMI and CPR did not change significantly in trained groups. In post test HS-CRP was significantly lower in trained groups in comparison to control group (P≤0.05). LDL, Cholesterol and cholesterol/HDL ratio decreased significantly in trained groups (P≤0.05). In the HI group plasma level of fibrinogen were decreased while HDL level were increased (P≤0.05).

Conclusion: Resistance training for 6 weeks in young healthy males evoked beneficial effects regarding some inflammatory and cardiovascular risk markers. Higher-intensity resistance training was more effective in reducing plasma fibrinogen and increasing plasma HDL levels than moderate resistance training.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Apolipoproteins A / blood
  • Apolipoproteins B / blood
  • Blood Pressure
  • Body Mass Index
  • C-Reactive Protein / metabolism
  • Cardiovascular Diseases / prevention & control*
  • Cholesterol / blood*
  • Cholesterol, HDL / blood
  • Cholesterol, LDL / blood
  • Fibrinogen / metabolism
  • Humans
  • Interleukin-1 / blood
  • Interleukin-6 / blood
  • Lipoprotein Lipase / blood
  • Male
  • Random Allocation
  • Resistance Training*
  • Risk Factors
  • Triglycerides / blood
  • Waist-Hip Ratio
  • Young Adult


  • Apolipoproteins A
  • Apolipoproteins B
  • Cholesterol, HDL
  • Cholesterol, LDL
  • Interleukin-1
  • Interleukin-6
  • Triglycerides
  • Fibrinogen
  • C-Reactive Protein
  • Cholesterol
  • Lipoprotein Lipase