Technical desiderata for the integration of genomic data into Electronic Health Records

J Biomed Inform. 2012 Jun;45(3):419-22. doi: 10.1016/j.jbi.2011.12.005. Epub 2011 Dec 27.


The era of "Personalized Medicine," guided by individual molecular variation in DNA, RNA, expressed proteins and other forms of high volume molecular data brings new requirements and challenges to the design and implementation of Electronic Health Records (EHRs). In this article we describe the characteristics of biomolecular data that differentiate it from other classes of data commonly found in EHRs, enumerate a set of technical desiderata for its management in healthcare settings, and offer a candidate technical approach to its compact and efficient representation in operational systems.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Databases, Factual
  • Delivery of Health Care
  • Electronic Health Records*
  • Genomics*
  • Humans
  • Precision Medicine / methods*