Power surge: supporting cells "fuel" cancer cell mitochondria

Cell Metab. 2012 Jan 4;15(1):4-5. doi: 10.1016/j.cmet.2011.12.011.


An emerging paradigm in tumor metabolism is that catabolism in host cells "fuels" the anabolic growth of cancer cells via energy transfer. A study in Nature Medicine (Nieman et al., 2011) supports this; they show that triglyceride catabolism in adipocytes drives ovarian cancer metastasis by providing fatty acids as mitochondrial fuels.

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