Effect of ethanol on the morphohistogenesis and differentiation of cerebellar granule cells in the chick embryo

Alcohol. 1990 Sep-Oct;7(5):419-28. doi: 10.1016/0741-8329(90)90026-9.

Abstract

In this present study we analyse, with the help of the Golgi method, the effect of ethanol on the morphological differentiation of the cerebellar granule cells in the chick embryo. Ethanol seems to affect the process of cell migration from the early stages of differentiation. Some granule cells appear to differentiate in an inverted position. These observations also confirm, on the basis of their axon morphology, the existence of three types of granule cells in the chick cerebellum.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Differentiation / drug effects
  • Cell Movement / drug effects
  • Cerebellum / drug effects*
  • Cerebellum / embryology
  • Cerebellum / ultrastructure
  • Chick Embryo
  • Cytoplasmic Granules / drug effects*
  • Cytoplasmic Granules / ultrastructure
  • Ethanol / toxicity*
  • Morphogenesis / drug effects

Substances

  • Ethanol