Variations in the brachial plexus and its terminal branches are not uncommon. A communicating branch arising from the musculocutaneous nerve to the median nerve is a frequent variation, but complete merging of musculocutaneous nerve into the median nerve is very rare. Here, we observed variations in the origin, course and distribution of the median nerve in the left upper limb. The musculocutaneous nerve was absent. The median nerve was formed in the upper part of the arm, in front of the brachial artery. The median nerve supplied the biceps, coracobrachialis and brachialis muscles and gave the lateral cutaneous nerve of the forearm. The present report provides evidence of variation in important nerves of the anterior compartment of the arm.