Differential firing patterns of the peptide-containing cholinergic motor neurons B15 and B16 during feeding behavior in Aplysia

Brain Res. 1990 Jul 2;522(1):176-9. doi: 10.1016/0006-8993(90)91598-b.


During egestive responses neuron B16 fires at 20 Hz, while neuron B15 is not active. During ingestive responses B16 fires for 0.5-1.0 s at 15-20 Hz, then B15 and B16 fire together, with B15 firing at 7.5-12 Hz. The duration of activity during ingestive responses depends on consumption of food: when food is not consumed, bursts are shorter (e.g. 2 vs 4 s). This study establishes a basis for investigating the role of peripheral neuromodulation under physiologically relevant conditions.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acetylcholine / pharmacology
  • Animals
  • Aplysia / physiology*
  • Electrophysiology
  • Feeding Behavior / physiology*
  • Motor Neurons / physiology*
  • Parasympathetic Nervous System / cytology
  • Parasympathetic Nervous System / physiology*
  • Synapses / drug effects


  • Acetylcholine