Endobronchial valves in the management of broncho-pleural and alveolo-pleural fistulae

Lung. 2012 Jun;190(3):347-51. doi: 10.1007/s00408-011-9369-1. Epub 2012 Jan 14.


Pneumothorax from bronchopleural or alveolo-pleural fistulae can be complicated by prolonged air leak (AL). This can occur in a variety of clinical settings. Examples include structural lung disease, such as bronchiectasis, and cavitary lung disorders. Prolonged AL is associated with prolonged hospital stay, atelectasis, pneumonia, and thromboembolic disease. Endobronchial valves (EBVs) have been recently introduced to manage such situations. The global experience in this novel therapeutic modality is still evolving. We report our preliminary experience with managing persistent AL treated successfully with EBVs and review the current literature on this subject. Our experience shows that EBVs are an effective tool for the management of prolonged AL from persistent bronchopleural or alveolo-pleural fistulae. It is a minimally invasive procedure recommended as an option, particularly in patients not fit for surgical repair.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bronchial Fistula / therapy
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pleural Diseases / therapy*
  • Pregnancy
  • Pregnancy Complications / therapy*
  • Prostheses and Implants*
  • Pulmonary Alveoli*
  • Respiratory Tract Fistula / therapy*