Idiopathic granulomatous lobular mastitis

Int J Dermatol. 2012 Feb;51(2):142-51. doi: 10.1111/j.1365-4632.2011.05168.x.


Idiopathic granulomatous lobular mastitis (IGLM) is a rare breast condition with prominent skin findings. It is typically seen in young parous women. Painful breast masses, draining sinuses, scarring, and breast atrophy are the main clinical manifestations. IGLM can resemble a variety of other inflammatory and neoplastic processes of the breast. It is thought to result from obstruction and rupture of breast lobules. Extravasated breast secretions then induce an inflammatory reaction. Corynebacteria have also been implicated in the pathogenesis. Treatment is surgical, but systemic corticosteroids, methotrexate, and antibiotics also play a role.

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Granulomatous Mastitis* / diagnosis
  • Granulomatous Mastitis* / etiology
  • Granulomatous Mastitis* / therapy
  • Humans
  • Prognosis