Dental implants in patients with Ehlers-Danlos syndrome: a case series study

Int J Prosthodont. Jan-Feb 2012;25(1):60-2.


Ehlers-Danlos syndrome (EDS) encompasses six types of hereditary connective tissue disorders, with skin hyperextensibility, joint hypermobility, and connective tissue fragility as the main findings. Oral health is also affected, sometimes including periodontitis and tooth loss. This is the first report on dental implant treatment for patients with hypermobility or classic EDS. Five female patients aged 19 to 68 years who tolerated treatment under local anesthesia and did not require bone augmentation were enrolled in the study and received 16 implants. They were observed for 2 to 12 years. No implants were lost, bone loss was minimal, and all patients were pleased with the treatment outcomes.

MeSH terms

  • Adult
  • Aged
  • Alveolar Bone Loss / diagnostic imaging
  • Crowns
  • Dental Implants*
  • Dental Prosthesis, Implant-Supported
  • Denture, Partial, Fixed
  • Ehlers-Danlos Syndrome / complications*
  • Esthetics, Dental
  • Female
  • Follow-Up Studies
  • Gingival Hemorrhage / classification
  • Humans
  • Middle Aged
  • Patient Satisfaction
  • Periodontal Index
  • Prospective Studies
  • Radiography, Bitewing
  • Speech / physiology
  • Survival Analysis
  • Tooth Loss / rehabilitation
  • Treatment Outcome
  • Young Adult


  • Dental Implants