Long-term (up to 20 years) effects of 50-Hz magnetic field exposure on blood chemistry parameters in healthy men

Clin Biochem. 2012 Apr;45(6):425-8. doi: 10.1016/j.clinbiochem.2011.12.020. Epub 2012 Jan 9.


Objectives: The potential effects of a chronic exposure to magnetic fields on blood chemistry in humanswere tested.

Design: We examined the nocturnal profiles and levels of the following blood parameters: electrolytes (sodium, potassium, chloride, calcium, magnesium, phosphorus), nonprotein nitrogenous compounds (uric acid, urea, creatinine), and glucose, in 15 men (38.0 ± 0.9 years) exposed chronically and daily for a period of 1-20 years, in the workplace and at home, to a 50-Hz magnetic field in search of any cumulative effect from those chronic conditions of exposure. The weekly geometric mean of individual exposures ranged from 0.1 to 2.6 μT. The results are compared to those obtained in our control group: 15 unexposed men of similar age (39.4 ± 1.2 years), with the same synchronization and physical activity that served as controls (individual exposures ranged from 0.004 to 0.092 μT). Blood samples were taken hourly from 20:00 h to 08:00 h.

Results: This work shows that subjects exposed over a long period (up to 20 years) and on a daily basis to magnetic fields experienced significant changes in serum sodium, chloride, phosphorus and glucose where an effect for field-hour interaction was noted for exposures greater than 0.3 μT.

Conclusion: Our data suggest that long-term exposure to 50-Hzmagnetic fields (exposure>0.3 μT) in healthy men could induce some biological modifications of certain blood parameters, though their clinical relevance needs further investigation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Analysis of Variance
  • Blood Glucose*
  • Case-Control Studies
  • Creatinine / blood
  • Electrolytes / blood*
  • Humans
  • Magnetic Fields* / adverse effects
  • Male
  • Men's Health
  • Middle Aged
  • Occupational Exposure* / adverse effects
  • Urea / blood
  • Uric Acid / blood


  • Blood Glucose
  • Electrolytes
  • Uric Acid
  • Urea
  • Creatinine