Discovery of selective alpha(2C) adrenergic receptor agonists

ChemMedChem. 2012 Mar 5;7(3):385-90. doi: 10.1002/cmdc.201100528. Epub 2012 Jan 19.
No abstract available

MeSH terms

  • Adrenergic alpha-2 Receptor Agonists / chemical synthesis*
  • Adrenergic alpha-2 Receptor Agonists / pharmacokinetics
  • Adrenergic alpha-2 Receptor Agonists / therapeutic use
  • Analgesics / chemical synthesis*
  • Analgesics / pharmacokinetics
  • Analgesics / therapeutic use
  • Animals
  • CHO Cells
  • Cricetinae
  • Drug Discovery
  • Humans
  • Neuralgia / drug therapy*
  • Neuralgia / physiopathology
  • Oxazoles / chemical synthesis*
  • Oxazoles / pharmacokinetics
  • Oxazoles / therapeutic use
  • Pain Measurement
  • Rats
  • Receptors, Adrenergic, alpha-2 / metabolism*

Substances

  • Adrenergic alpha-2 Receptor Agonists
  • Analgesics
  • Oxazoles
  • Receptors, Adrenergic, alpha-2