α,β-Unsaturated imines via Ru-catalyzed coupling of allylic alcohols and amines

Org Biomol Chem. 2012 Mar 7;10(9):1746-9. doi: 10.1039/c2ob06921k. Epub 2012 Jan 20.

Abstract

A convenient synthesis of α,β-unsaturated imines requiring only an allylic alcohol, an amine and a Ru catalyst has been developed. The use of large excesses of oxidant and the purification of sensitive intermediates can be avoided.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amines / chemistry*
  • Catalysis
  • Imines / chemistry*
  • Isomerism
  • Ligands
  • Molecular Structure
  • Oxidation-Reduction
  • Propanols / chemistry*
  • Ruthenium / chemistry*

Substances

  • Amines
  • Imines
  • Ligands
  • Propanols
  • allyl alcohol
  • Ruthenium