How to use insulin-like growth factor 1 (IGF1)

Arch Dis Child Educ Pract Ed. 2012 Jun;97(3):114-8. doi: 10.1136/archdischild-2011-300265. Epub 2012 Jan 20.

Abstract

Insulin-like growth factor 1 (IGF1) is produced in the liver and peripheral tissues including the growth plate, in response to growth hormone (GH) and is commonly used as a diagnostic marker of growth hormone deficiency (GHD) and to monitor GH replacement therapy, as recommended by an international GH consensus.1 However, while it is a useful biochemical tool, there are limitations to its use and results should be interpreted with care.

MeSH terms

  • Growth Disorders / blood
  • Growth Disorders / diagnosis
  • Growth Disorders / drug therapy*
  • Growth Hormone / therapeutic use
  • Humans
  • Insulin-Like Growth Factor I / analysis*
  • Insulin-Like Growth Factor I / therapeutic use*
  • Reference Values

Substances

  • Insulin-Like Growth Factor I
  • Growth Hormone