Yes, even human brown fat is on fire!

J Clin Invest. 2012 Feb;122(2):486-9. doi: 10.1172/JCI60941. Epub 2012 Jan 24.

Abstract

That adult humans possess brown fat is now accepted - but is the brown fat metabolically active? Does human brown fat actually combust fat to release heat? In this issue of the JCI, Ouellet et al. demonstrate that metabolism in brown fat really is increased when adult humans are exposed to cold. This boosts the possibility that calorie combustion in brown fat may be of significance for our metabolism and, correspondingly, that the absence of brown fat may increase our proneness to obesity - provided that brown fat becomes activated not only by cold but also through food-related stimuli.

Publication types

  • Comment

MeSH terms

  • Adipose Tissue, Brown / metabolism*
  • Animals
  • Cold Temperature*
  • Energy Metabolism / physiology*
  • Humans
  • Male
  • Thermogenesis / physiology*