In vivo UVB-photoprotective activity of extracts from commercial marine macroalgae

Food Chem Toxicol. 2012 Mar;50(3-4):1109-17. doi: 10.1016/j.fct.2012.01.004. Epub 2012 Jan 18.


The photoprotective potential against UVB radiation of extracts obtained from 21 commercial macroalgae from the Phyla Ochrophyta and Rhodophyta, was evaluated in vivo, using the zebrafish embryo as a whole model organism. Our results showed that the phenolic extracts from Macrocystis pyrifera and Porphyra columbina exhibited the highest photoprotective activity, close to complete photoprotection (100%), similar to that obtained for the carrageenophytes Sarcothalia radula and Gigartina skottsbergii. Under the assayed conditions, the extracts were safe and non-toxic to the embryos at a concentration of 0.04 mg/ml PGE.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Marine Biology*
  • Microalgae / chemistry*
  • Plant Extracts / pharmacology*
  • Polyphenols / isolation & purification
  • Radiation-Protective Agents / pharmacology*
  • Ultraviolet Rays*
  • Zebrafish / embryology


  • Plant Extracts
  • Polyphenols
  • Radiation-Protective Agents