Crystal structure and fluorescence studies reveal the role of helical dimeric interface of staphylococcal FabG1 in positive cooperativity for NADPH

Proteins. 2012 Apr;80(4):1250-7. doi: 10.1002/prot.24024. Epub 2012 Feb 10.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase
  • Alcohol Oxidoreductases / chemistry*
  • Alcohol Oxidoreductases / genetics
  • Bacterial Proteins / chemistry*
  • Bacterial Proteins / genetics
  • Cloning, Molecular
  • Crystallization
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • Escherichia coli / chemistry
  • Escherichia coli / genetics
  • Fluorescence
  • NADP / chemistry*
  • Protein Binding
  • Protein Interaction Mapping
  • Protein Multimerization
  • Protein Structure, Secondary
  • Spectrometry, Fluorescence
  • Staphylococcus aureus / chemistry*
  • Staphylococcus aureus / genetics
  • Tryptophan / chemistry

Substances

  • Bacterial Proteins
  • DNA, Bacterial
  • NADP
  • Tryptophan
  • Alcohol Oxidoreductases
  • 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase