Financial strain and impaired fasting glucose: the moderating role of physical activity in the Coronary Artery Risk Development in Young Adults study

Psychosom Med. 2012 Feb-Mar;74(2):187-92. doi: 10.1097/PSY.0b013e3182448d74. Epub 2012 Jan 27.


Objectives: Physical activity and financial strain are independent, and opposite, predictors of disease. This study examines whether physical activity modifies the concurrent and prospective relation between financial strain and impaired fasting glucose.

Methods: Participants were part of the Coronary Artery Risk Development in Young Adults study, a prospective study examining the development of disease. Participants were recruited in 1985 to 1986 and followed up for 20 years. The outcome measures were fasting glucose (FG) levels at Years 7 and 20. FG was available at Years 7 and 20 from 3991 and 3500 participants, respectively.

Results: The effects of financial strain on elevated glucose levels differed by physical activity levels as indicated by the significant interaction terms for the analyses of covariance at Year 7 (p = .02) and Year 20 (p = .04). Planned contrast comparisons demonstrated that FG levels in financially strained participants who were physically inactive were significantly different from financially strained participants who were active, and all participants with low financial strain. Specifically, in less active participants, the adjusted mean FG levels were higher in financially strained participants (2.27 mg/dL at Year 7 and 5.86 mg/dL at Year 20). In active participants, these differences were -1.78 mg/dL at Year 7 and negligible at Year 20.

Conclusions: In adults burdened by financial strain, physical activity is associated with a reduced risk of developing impaired FG up to 13 years later. This adds to a growing literature showing the potential of physical activity to moderate stress-related disease processes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Blood Glucose / metabolism*
  • Coronary Artery Disease / epidemiology*
  • Coronary Artery Disease / metabolism
  • Coronary Artery Disease / prevention & control
  • Fasting
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Motor Activity*
  • Poverty*
  • Prospective Studies
  • Risk Factors
  • Socioeconomic Factors
  • Stress, Psychological / epidemiology*
  • Young Adult


  • Blood Glucose