Pre-operative factors predicting good outcome in terms of health-related quality of life after ACL reconstruction

Scand J Med Sci Sports. 2013 Feb;23(1):15-22. doi: 10.1111/j.1600-0838.2011.01426.x. Epub 2012 Jan 31.


The life situation of many patients changes after an anterior cruciate ligament (ACL) rupture and subsequent reconstruction, and this may affect their health-related quality of life in many ways. It is well known that the overall clinical results after ACL reconstruction are considered good, but pre-operative predictive factors for a good post-operative clinical outcome after ACL reconstruction have not been studied in as much detail. The purpose of this study was to identify pre-operative factors that predict a good post-operative outcome as measured by the Short Form 36 (SF-36) and Knee Osteoarthritis Outcome Score (KOOS) 3-6 years after ACL reconstruction. Seventy-three patients scheduled for ACL reconstruction were clinically examined pre-operatively. The SF-36 and KOOS questionnaires were sent by mail to these patients 3-6 years after reconstruction. Predictive factors for health-related quality of life were investigated using a stepwise regression analysis. In conclusion, pre-operative factors, such as pivot shift, knee function, and range of motion, may predict a good post-operative outcome and explain up to 25% in terms of health-related quality of life after ACL reconstruction. Furthermore, it appears that the patients' pre-injury and pre-operative Tegner activity levels are important predictors of post-operative health-related quality of life.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anterior Cruciate Ligament Reconstruction / methods
  • Anterior Cruciate Ligament Reconstruction / rehabilitation*
  • Female
  • Humans
  • Knee Joint / physiology
  • Male
  • Motor Activity / physiology
  • Multivariate Analysis
  • Pain Measurement
  • Preoperative Period
  • Prognosis
  • Quality of Life*
  • Range of Motion, Articular / physiology*
  • Recovery of Function / physiology*
  • Regression Analysis
  • Sickness Impact Profile
  • Young Adult