Ischaemic stroke and influenza A H1N1 vaccination: a case report

Arch Med Sci. 2011 Apr;7(2):345-8. doi: 10.5114/aoms.2011.22090. Epub 2011 May 17.


We report a 75-year-old male patient who suffered posterior circulation ischaemia after influenza A/H1N1 vaccination. Vaccination provokes a variable magnitude of inflammatory and immunological response that modifies the risk for ischaemic stroke. Whereas a causal relation between vaccination and ischaemic stroke is still unsettled, an inflammatory/immunological response after vaccination may trigger thrombosis superimposing a pre-existing prothrombotic state. Careful monitoring is strongly suggested for individuals who received H1N1 vaccine, especially those with high ischaemic stroke risk.

Keywords: cerebellum; influenza A/H1N1; ischaemic stroke; risk factor; thrombosis; vaccine.

Publication types

  • Case Reports