Treatment of Heyde's Syndrome by Aortic Valve Replacement

Curr Cardiol Rev. 2011 Feb;7(1):47-9. doi: 10.2174/157340311795677699.


Heyde's syndrome is the association between calcific aortic stenosis and gastrointestinal bleeding due to angiodysplasia. Alterations in von Willebrand factor due to turbulence across the diseased aortic valve have been incriminated in the pathophysiology of this syndrome. Replacement of the aortic valve has been reported to stop the bleeding, but this is debatable. Along with a review of the relevant medical literature, we hereby report a 68 year old patient with aortic stenosis and severe recurrent gastrointestinal bleeding that completely subsided following aortic valve replacement.

Keywords: Aortic valve; angiodysplasia; bleeding.; gastrointestinal hemorrhage; von willebrand.