doi: 10.1126/science.1215369.
Nanoscopy in a living mouse brain
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- PMID: 22301313
- DOI: 10.1126/science.1215369
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Nanoscopy in a living mouse brain
Science.
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Abstract
We demonstrated superresolution optical microscopy in a living higher animal. Stimulated emission depletion (STED) fluorescence nanoscopy reveals neurons in the cerebral cortex of a mouse with <70-nanometer resolution. Dendritic spines and their subtle changes can be observed at their relevant scales over extended periods of time.
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