ST-segment elevation myocardial infarction in a 37-year-old man with normal coronaries--it is not always cocaine!

Am J Emerg Med. 2012 Nov;30(9):2091.e3-5. doi: 10.1016/j.ajem.2011.12.033. Epub 2012 Feb 4.


Heart disease is one of the leading causes of death in the United States. With the increase in substance abuse, the incidence of acute myocardial infarction (MI) in younger population has been on the rise. Traditionally, cocaine has been blamed for acute MI; however, recently, there have been more incidences of marijuana as an inciting factor. We present a case of marijuana-induced acute MI and discuss the proposed mechanism.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Chest Pain / etiology
  • Cocaine-Related Disorders / complications
  • Coronary Angiography
  • Electrocardiography
  • Emergency Service, Hospital
  • Humans
  • Male
  • Marijuana Smoking / adverse effects*
  • Myocardial Infarction / chemically induced*
  • Myocardial Infarction / physiopathology
  • Phosphodiesterase 5 Inhibitors / adverse effects
  • Piperazines / adverse effects
  • Purines / adverse effects
  • Sildenafil Citrate
  • Sulfones / adverse effects


  • Phosphodiesterase 5 Inhibitors
  • Piperazines
  • Purines
  • Sulfones
  • Sildenafil Citrate