Seroepidemiology of human bocavirus in Apulia, Italy

Clin Microbiol Infect. 2012 Apr;18(4):E74-6. doi: 10.1111/j.1469-0691.2011.03756.x. Epub 2012 Feb 6.

Abstract

A serological survey was performed to determine the prevalence of antibodies against human bocavirus in an Apulian population. Anti-hBoV IgG antibodies were analysed in 1206 inhabitants (age range, 1month-84years) using a standardized ELISA test based on the use of recombinant hBoV VP2 virus-like particles. In total, 1075 (89.1%) of 1206 participants (mean age 32±24.8years) displayed anti-hBoV-IgG. The seroprevalence increased significantly (p<0.0001) in children from 2-4years (64.2%) to 5-9years (96.4%). A similar trend was observed in both male and female subjects. In conclusion, our results show that hBoV infection is common in this population, especially in children.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antibodies, Viral / blood*
  • Antigens, Viral / immunology
  • Capsid Proteins / immunology
  • Child
  • Child, Preschool
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Human bocavirus / immunology*
  • Human bocavirus / isolation & purification
  • Human bocavirus / pathogenicity
  • Humans
  • Immunoglobulin G / blood
  • Infant
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Parvoviridae Infections / epidemiology*
  • Parvoviridae Infections / immunology
  • Parvoviridae Infections / virology
  • Prevalence
  • Seroepidemiologic Studies
  • Young Adult

Substances

  • Antibodies, Viral
  • Antigens, Viral
  • Capsid Proteins
  • Immunoglobulin G