Recurrence of acoustic neurilemoma as a malignant spindle-cell neoplasm. Case report

J Neurosurg. 1990 Dec;73(6):946-50. doi: 10.3171/jns.1990.73.6.0946.


A 75-year-old man presented with a right cerebellopontine angle tumor 11 months after complete macroscopic resection of a right acoustic neurilemoma. Histological examination of the recurrent tumor showed a malignant spindle-cell neoplasm with positive staining for S-100 protein. The patient had no stigmata of von Recklinghausen's disease. It is proposed that this recurrence represents progression from a benign to a malignant acoustic nerve-sheath tumor, an event that is extremely rare outside the clinicopathological context of neurofibromatosis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma / pathology*
  • Humans
  • Male
  • Neoplasm Recurrence, Local / pathology*
  • Neuroma, Acoustic / pathology*
  • Neuroma, Acoustic / surgery