Twelve-month outcomes of the loozit randomized controlled trial: a community-based healthy lifestyle program for overweight and obese adolescents

Arch Pediatr Adolesc Med. 2012 Feb;166(2):170-7. doi: 10.1001/archpediatrics.2011.841.


Objectives: To assess the outcomes of the Loozit adolescent weight management intervention and to evaluate the effect of additional therapeutic contact 12 months into the program.

Design: A 24-month, 2-arm randomized controlled trial. Results at 12 months are presented.

Setting: Community health center and children's hospital in Sydney, Australia.

Participants: A total of 151 overweight or obese 13- to 16-year-olds.

Intervention: In the first 2 months (phase 1), participants received 7 adolescent and parent weekly sessions focused on lifestyle modification. From 2 to 24 months (phase 2), adolescents attended booster sessions once every 3 months. During phase 2, adolescents randomized to the additional therapeutic contact arm also received telephone coaching and electronic communications once every 2 weeks.

Outcome measures: Baseline to 12-month changes in body mass index z score and waist to height ratio (primary outcomes) and changes in metabolic, psychosocial, and behavioral variables.

Results: Of 151 randomized adolescents, 82.1% completed 12-month follow-up. Intent-to-treat analyses showed significant reductions in mean body mass index z score (-0.09; 95% CI, -0.12 to -0.06), waist to height ratio (-0.02; 95% CI, -0.03 to -0.01), total cholesterol level (-4 mg/dL; 95% CI, -8 to 0 mg/dL; to convert to millimoles per liter, multiply by 0.0259), and triglycerides level (geometric mean, -80 mg/dL; 95% CI, -88 to -71 mg/dL; to convert to millimoles per liter, multiply by 0.0113). Most psychosocial outcomes improved, including global self-worth, but there were few dietary, physical activity, or sedentary behavior changes. No difference was found in primary outcomes between participants who did or did not receive additional therapeutic contact.

Conclusions: The Loozit randomized controlled trial produced a significant but modest reduction in body mass index z score and improved psychosocial outcomes at 12 months. Supplementary telephone and electronic contact provided no additional benefit at 12 months. Trial Registration Identifier: 12606000175572.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adolescent Behavior*
  • Australia
  • Body Height
  • Body Mass Index
  • Cholesterol / blood
  • Cognitive Behavioral Therapy / methods*
  • Counseling
  • Female
  • Health Behavior*
  • Humans
  • Life Style
  • Male
  • Obesity / psychology
  • Obesity / therapy*
  • Outcome Assessment, Health Care
  • Overweight / psychology
  • Overweight / therapy*
  • Self Concept
  • Telephone
  • Triglycerides / blood
  • Waist Circumference


  • Triglycerides
  • Cholesterol