Bee-honey and yogurt: a novel mixture for treating patients with vulvovaginal candidiasis during pregnancy

Arch Gynecol Obstet. 2012 Jul;286(1):109-14. doi: 10.1007/s00404-012-2242-5. Epub 2012 Feb 8.

Abstract

Objective: To evaluate the clinical and mycological cure rates of a novel mixture consisting of Bee-honey and yogurt compared to local antifungal agents for treating patients with vulvo-vaginal candidiasis (VVC) during pregnancy.

Materials and methods: This is a prospective comparative study which included 129 patients with VVC during pregnancy. The participants were allocated into study group (n = 82) who received a mixture of Bee-honey and yogurt vaginally and control group (n = 47) who received local anti-fungal agents. The Chi-square test was used to evaluate the clinical and mycological cure rates and the side-effects of both modes of therapy.

Results: The clinical cure rate was significantly higher in the study than the control group (87.8 vs. 72.3%, respectively) while the mycological cure rate was higher in the control than the study group (91.5 vs. 76.9%, respectively). Both types of therapy were favorably tolerated by most of the patients. Side effects were reported only in 24.3 and 29.7% of patients in group I and II, respectively (p < 0.05).

Conclusions: The mixture of Bee-honey and yogurt produced a high clinical cure rate and a reasonable mycological cure rate. It can be used as a complementary or an alternative to antifungal agents especially in patients with VVC during pregnancy.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Administration, Intravaginal
  • Adult
  • Animals
  • Bees
  • Candida / isolation & purification
  • Candidiasis, Vulvovaginal / diagnosis
  • Candidiasis, Vulvovaginal / microbiology
  • Candidiasis, Vulvovaginal / therapy*
  • Female
  • Honey*
  • Humans
  • Middle Aged
  • Prospective Studies
  • Treatment Outcome
  • Yogurt*