Optineurin immunoreactivity in neuronal nuclear inclusions of polyglutamine diseases (Huntington's, DRPLA, SCA2, SCA3) and intranuclear inclusion body disease

Acta Neuropathol. 2012 May;123(5):747-9. doi: 10.1007/s00401-012-0956-x. Epub 2012 Feb 9.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Diseases / metabolism*
  • Brain Diseases / pathology*
  • Cell Cycle Proteins
  • Frontal Lobe / pathology*
  • Humans
  • Huntington Disease
  • Intranuclear Inclusion Bodies / pathology*
  • Machado-Joseph Disease
  • Membrane Transport Proteins
  • Myoclonic Epilepsies, Progressive
  • Neurodegenerative Diseases
  • Neurons / metabolism*
  • Peptides / metabolism
  • Postmortem Changes
  • Spinocerebellar Ataxias
  • Transcription Factor TFIIIA / metabolism*

Substances

  • Cell Cycle Proteins
  • Membrane Transport Proteins
  • OPTN protein, human
  • Peptides
  • Transcription Factor TFIIIA
  • polyglutamine