The value of leak pressure and bladder compliance in the urodynamic evaluation of meningomyelocele patients

J Urol. 1990 Dec;144(6):1440-2. doi: 10.1016/s0022-5347(17)39761-6.


A total of 61 patients with myelodysplasia underwent water cystometry and electromyography of the external sphincter. Of these patients 27 underwent video fluorourodynamics as a part of preoperative evaluation or instead of a voiding cystometrogram. Renal quantitative scintillation camera studies detected 7 patients with mild upper tract deterioration, even when other tests failed to do so. A total of 31 patients had upper tract deterioration as detected by excretory urography, ultrasound and/or renal scan studies, and were designated as group 1, while 30 had normal upper tracts and were designated as group 2. Bladder compliance in group 1 was significantly lower than that in group 2 (4.5 versus 11.3 ml./cm. water, p = 0.001). Leak pressure in group 1 was significantly higher than in group 2 (42.3 versus 26.1 cm. water, p = 0.019). In summary, patients with evidence of upper tract deterioration had lower bladder compliance and higher leak pressure than patients with normal kidneys.

MeSH terms

  • Child
  • Electromyography
  • Female
  • Humans
  • Male
  • Meningomyelocele / physiopathology*
  • Pressure
  • Urinary Bladder / physiopathology*
  • Urinary Bladder, Neurogenic / diagnosis*
  • Urinary Bladder, Neurogenic / etiology
  • Urinary Bladder, Neurogenic / physiopathology
  • Urodynamics / physiology*