Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules

Immunogenetics. 2012 Jun;64(6):455-60. doi: 10.1007/s00251-012-0599-z. Epub 2012 Feb 10.


Celiac disease is caused by an abnormal intestinal T-cell response to gluten proteins of wheat, barley and rye. Over the last few years, a number of gluten T-cell epitopes restricted by celiac disease associated HLA-DQ molecules have been characterized. In this work, we give an overview of these epitopes and suggest a comprehensive, new nomenclature.

Publication types

  • Review

MeSH terms

  • Celiac Disease / etiology*
  • Epitopes, T-Lymphocyte / immunology*
  • Glutens / immunology*
  • HLA-DQ Antigens / immunology*
  • Humans
  • Terminology as Topic*


  • Epitopes, T-Lymphocyte
  • HLA-DQ Antigens
  • Glutens