A practical critique of antifungal treatment guidelines for haemato-oncologists

Crit Rev Microbiol. 2012 Aug;38(3):203-16. doi: 10.3109/1040841X.2011.645521. Epub 2012 Feb 11.

Abstract

The management of invasive fungal disease (IFD) in the haemato-oncology setting remains a challenge. This article reviews recent guidelines relating to IFD for their similarities and differences, as well as applying the Appraisal of Guidelines Research and Evaluation (AGREE) criteria. The guidelines' recommendations on antifungal prophylaxis, empirical and definitive treatment of candidiasis and aspergillosis are summarized; also, minimum standards for diagnosis and follow-up are discussed. This critique of the reviewed guidelines is a practical guide to physicians and commissioners in making local policies for IFD management.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antifungal Agents / therapeutic use*
  • Candidiasis, Invasive / diagnosis
  • Candidiasis, Invasive / drug therapy*
  • Candidiasis, Invasive / prevention & control
  • Chemoprevention / methods
  • Hematologic Neoplasms / complications*
  • Hematologic Neoplasms / drug therapy
  • Humans
  • Immunocompromised Host
  • Invasive Pulmonary Aspergillosis / diagnosis
  • Invasive Pulmonary Aspergillosis / drug therapy*
  • Invasive Pulmonary Aspergillosis / prevention & control
  • Practice Guidelines as Topic

Substances

  • Antifungal Agents