Capturing a virus while it catches its breath

Structure. 2012 Feb 8;20(2):200-2. doi: 10.1016/j.str.2012.01.014.


The four serotypes of dengue virus present a formidable challenge for the development of efficacious human vaccines. Cockburn and colleagues, in this issue of Structure, describe the structural basis of a cross-reactive neutralizing antibody, providing greater insight into immune protection and pathogenesis.

Publication types

  • Comment

MeSH terms

  • Animals
  • Antibodies, Monoclonal, Murine-Derived / chemistry*
  • Antibodies, Neutralizing / chemistry*
  • Antiviral Agents / chemistry*
  • Dengue Virus / immunology*
  • Humans
  • Viral Envelope Proteins / chemistry*


  • Antibodies, Monoclonal, Murine-Derived
  • Antibodies, Neutralizing
  • Antiviral Agents
  • Viral Envelope Proteins