The effect of social determinants on immunization programs

Hum Vaccin Immunother. 2012 Mar;8(3):293-301. doi: 10.4161/hv.19003. Epub 2012 Feb 13.


Vaccine preventable diseases have been responsible for a significant portion of childhood mortality in low-income countries, and have been re-emerging in medium- and high-income countries. The effectiveness of routine childhood immunization programs relies on multiple factors. Social determinants have the potential to affect immunization programs around the world, with globalization and ease of communication facilitating their effect. Exploring the types of social determinants affecting immunization efforts in various countries is of great importance to the ability of nations to address them, prevent the spread of disease and lower mortality rates. The social determinants affecting vaccination programs can vary among countries of different income levels, with some social determinants overlapping among these country groups. In this article we explore the various social determinants affecting routine immunization programs in low-, middle- and high-income countries and possible interventions to address them.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Communicable Diseases / epidemiology*
  • Developed Countries
  • Developing Countries
  • Global Health
  • Humans
  • Immunization Programs*
  • Socioeconomic Factors
  • Vaccination / methods*
  • Vaccination / statistics & numerical data*