[Morphological and histochemical analysis of mucous membrane transformation of the artificial urinary bladder]

Tsitol Genet. 2011 Nov-Dec;45(6):3-9.
[Article in Russian]

Abstract

The performed morphologic study of transformation mechanisms of the intestinal reservoir mucous membrane using modern immunochemical and histochemical methods revealed three morphologic phases of enteric epithelium adaptation; reactive-inflammatory, compensatory-protective and atrophic. Enteric urinary reservoir preserves the cambial apparatus typical for the enteric phenotype with an inherent apoptosis activity and proliferation which confirms a low level of tumor transformation risk.

Publication types

  • English Abstract

MeSH terms

  • Adaptation, Physiological*
  • Artificial Organs*
  • Biomarkers / analysis
  • Biopsy
  • Cell Differentiation
  • Cell Proliferation
  • Cystectomy*
  • Humans
  • Ileum / cytology*
  • Ileum / metabolism
  • Immunohistochemistry
  • Intestinal Mucosa / cytology*
  • Intestinal Mucosa / metabolism
  • Ki-67 Antigen / analysis
  • Ki-67 Antigen / biosynthesis
  • Male
  • Metaplasia
  • Mucous Membrane / cytology*
  • Mucous Membrane / metabolism
  • Tumor Suppressor Protein p53 / analysis
  • Tumor Suppressor Protein p53 / biosynthesis
  • Urinary Bladder / pathology*
  • Urinary Bladder / surgery
  • bcl-Associated Death Protein / analysis
  • bcl-Associated Death Protein / biosynthesis

Substances

  • Biomarkers
  • Ki-67 Antigen
  • Tumor Suppressor Protein p53
  • bcl-Associated Death Protein