Electrophysiological analysis of circuits controlling energy homeostasis

Mol Neurobiol. 2012 Apr;45(2):258-78. doi: 10.1007/s12035-012-8241-5. Epub 2012 Feb 14.

Abstract

Since the discovery of leptin and the central melanocortin circuit, electrophysiological studies have played a major role in elucidating mechanisms underlying energy homeostasis. This review highlights the contribution of findings made by electrophysiological measurements to the current understanding of hypothalamic neuronal networks involved in energy homeostasis with a specific focus on the arcuate-paraventricular nucleus circuit.

Publication types

  • Review

MeSH terms

  • Animals
  • Appetite Regulation / physiology
  • Electrophysiology / methods
  • Energy Metabolism / physiology*
  • Homeostasis / physiology*
  • Humans
  • Hypothalamus / anatomy & histology
  • Hypothalamus / physiology*
  • Neural Pathways / anatomy & histology
  • Neural Pathways / physiology
  • Neuropeptides / physiology*
  • Receptors, Neuropeptide / physiology
  • Signal Transduction / physiology

Substances

  • Neuropeptides
  • Receptors, Neuropeptide